HCSGD entry for TPSAB1

1. General information

Official gene symbolTPSAB1
Entrez ID7177
Gene full nametryptase alpha/beta 1
Other gene symbolsTPS1 TPS2 TPSB1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIEA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006952Defense responseTASbiological_process
GO:0008236Serine-type peptidase activityTASmolecular_function
GO:0022617Extracellular matrix disassemblyTASbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0031012Extracellular matrixIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.92133635120.81670569510.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0172813326
GSE13712_SHEARUp0.0436408363
GSE13712_STATICDown-0.0779010224
GSE19018Up0.1255397984
GSE19899_A1Down-0.0292007112
GSE19899_A2Up0.0254149833
PubMed_21979375_A1Down-0.1643441335
PubMed_21979375_A2Down-0.1388651688
GSE35957Up0.0491612947
GSE36640Down-0.0614946398
GSE54402Up0.0068095441
GSE9593Up0.0251085668
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0275350632

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Amido Phenyl Pyruvic AcidDB02018 EXPT00537
4-PIPERIDIN-4-YLBUTANALDB04654 -
[4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONEDB04764 -
(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanoneDB06962 -
1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamineDB06848 -
1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamineDB06849 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.