HCSGD entry for TYRP1

1. General information

Official gene symbolTYRP1
Entrez ID7306
Gene full nametyrosinase-related protein 1
Other gene symbolsCAS2 CATB GP75 OCA3 TRP TRP1 TYRP b-PROTEIN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005507Copper ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0010008Endosome membraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016716Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygenIEAmolecular_function
GO:0030318Melanocyte differentiationIEAbiological_process
GO:0030669Clathrin-coated endocytic vesicle membraneIDAcellular_component
GO:0032438Melanosome organizationIEAbiological_process
GO:0033162Melanosome membraneIEA ISScellular_component
GO:0042438Melanin biosynthetic processIEAbiological_process
GO:0042470MelanosomeISScellular_component
GO:0042803Protein homodimerization activityIEA ISSmolecular_function
GO:0043438Acetoacetic acid metabolic processIEAbiological_process
GO:0046982Protein heterodimerization activityIEA ISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01183760120.97259837010.27291144101.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.5993000652
GSE13712_SHEARDown-0.0344797017
GSE13712_STATICDown-0.1889589543
GSE19018Up0.5537615008
GSE19899_A1Up0.6555154611
GSE19899_A2Up0.1217149824
PubMed_21979375_A1Down-0.3536642220
PubMed_21979375_A2Up0.7112392723
GSE35957Up0.1735027376
GSE36640Up1.6221615294
GSE54402Up0.7989990410
GSE9593Up0.0115685217
GSE43922Up0.1782385323
GSE24585Up0.1702759828
GSE37065Down-0.0049390713
GSE28863_A1Up0.0216193299
GSE28863_A2Up0.0007964782
GSE28863_A3Up0.0106366815
GSE28863_A4Up0.0440077280
GSE48662Up0.0336922149

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.