HCSGD entry for UBE2V2
1. General information
| Official gene symbol | UBE2V2 |
|---|---|
| Entrez ID | 7336 |
| Gene full name | ubiquitin-conjugating enzyme E2 variant 2 |
| Other gene symbols | DDVIT1 DDVit-1 EDAF-1 EDPF-1 EDPF1 MMS2 UEV-2 UEV2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000209 | Protein polyubiquitination | TAS | biological_process |
| GO:0000729 | DNA double-strand break processing | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0006282 | Regulation of DNA repair | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0010976 | Positive regulation of neuron projection development | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | TAS | biological_process |
| GO:0016881 | Acid-amino acid ligase activity | IEA | molecular_function |
| GO:0031372 | UBC13-MMS2 complex | IDA | cellular_component |
| GO:0032436 | Positive regulation of proteasomal ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0043524 | Negative regulation of neuron apoptotic process | IEA | biological_process |
| GO:0045739 | Positive regulation of DNA repair | IEA | biological_process |
| GO:0051965 | Positive regulation of synapse assembly | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9228442650 | 0.1389133999 | 0.9999902473 | 0.7173633778 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4665119418 |
| GSE13712_SHEAR | Up | 0.0423417977 |
| GSE13712_STATIC | Up | 0.0469208491 |
| GSE19018 | Down | -0.3339638122 |
| GSE19899_A1 | Up | 0.1063227421 |
| GSE19899_A2 | Down | -0.0622119231 |
| PubMed_21979375_A1 | Up | 0.5905770362 |
| PubMed_21979375_A2 | Up | 0.3473466984 |
| GSE35957 | Down | -0.2966118979 |
| GSE36640 | Down | -0.5760397001 |
| GSE54402 | Up | 0.1742736291 |
| GSE9593 | Down | -0.3606096838 |
| GSE43922 | Up | 0.0061393401 |
| GSE24585 | Down | -0.2435465361 |
| GSE37065 | Down | -0.0946078292 |
| GSE28863_A1 | Up | 0.0094038222 |
| GSE28863_A2 | Up | 0.0506516074 |
| GSE28863_A3 | Down | -0.0434894301 |
| GSE28863_A4 | Down | -0.0787298925 |
| GSE48662 | Down | -0.2287914576 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024376 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026382 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029206 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051590 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
