HCSGD entry for WAS

1. General information

Official gene symbolWAS
Entrez ID7454
Gene full nameWiskott-Aldrich syndrome
Other gene symbolsIMD2 SCNX THC THC1 WASP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0005083Small GTPase regulator activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0006461Protein complex assemblyTASbiological_process
GO:0006952Defense responseTASbiological_process
GO:0006955Immune responseIMPbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008154Actin polymerization or depolymerizationTASbiological_process
GO:0008544Epidermis developmentTASbiological_process
GO:0012506Vesicle membraneIEAcellular_component
GO:0015629Actin cytoskeletonTAScellular_component
GO:0016197Endosomal transportIEAbiological_process
GO:0030041Actin filament polymerizationIEAbiological_process
GO:0030048Actin filament-based movementIEAbiological_process
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosisTASbiological_process
GO:0042110T cell activationIEAbiological_process
GO:0042802Identical protein bindingIEA IPImolecular_function
GO:0045087Innate immune responseTASbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:2000601Positive regulation of Arp2/3 complex-mediated actin nucleationIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23226881580.93794244900.91579348411.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0610403820
GSE13712_SHEARUp0.1070431969
GSE13712_STATICUp0.1454080840
GSE19018Up0.1070588636
GSE19899_A1Up0.0111822725
GSE19899_A2Up0.2029156086
PubMed_21979375_A1Up0.1343912266
PubMed_21979375_A2Up0.0003240913
GSE35957Down-0.0628250348
GSE36640Down-0.0355815169
GSE54402Down-0.0588912052
GSE9593Down-0.0086935872
GSE43922Up0.1069623924
GSE24585Down-0.0342555071
GSE37065Up0.0703035951
GSE28863_A1Down-0.1510798971
GSE28863_A2Down-0.0764853278
GSE28863_A3Up0.4306444115
GSE28863_A4Up0.1299014468
GSE48662Up0.8074283659

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

(S)-WiskostatinDB01731 EXPT03245

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.