HCSGD entry for ZNF85


1. General information

Official gene symbolZNF85
Entrez ID7639
Gene full namezinc finger protein 85
Other gene symbolsHPF4 HTF1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.93243834580.01821146990.99999024730.2639560022

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1246503048
GSE13712_SHEARUp0.2765267207
GSE13712_STATICUp0.1719368104
GSE19018Down-0.0359360861
GSE19899_A1Down-0.0583112927
GSE19899_A2Down-1.7176791185
PubMed_21979375_A1Down-0.8112403477
PubMed_21979375_A2Down-1.6376680814
GSE35957Down-0.8433304549
GSE36640Down-1.2802064231
GSE54402Down-0.2793846655
GSE9593Down-0.3606227388
GSE43922Down-0.1483523162
GSE24585Up0.2657428771
GSE37065Up0.0016918737
GSE28863_A1Up0.0673768856
GSE28863_A2Up0.0526679543
GSE28863_A3Down-0.0212365994
GSE28863_A4Down-0.0294369160
GSE48662Up0.0418663730

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024843MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026711MicroarrayFunctional MTI (Weak)19074876
hsa-miR-26b-5pMIMAT0000083MIRT029822MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.