HCSGD entry for TRIM25
1. General information
| Official gene symbol | TRIM25 |
|---|---|
| Entrez ID | 7706 |
| Gene full name | tripartite motif containing 25 |
| Other gene symbols | EFP RNF147 Z147 ZNF147 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0030054 | Cell junction | IDA | cellular_component |
| GO:0032480 | Negative regulation of type I interferon production | TAS | biological_process |
| GO:0033280 | Response to vitamin D | IEA | biological_process |
| GO:0043627 | Response to estrogen | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:2001141 | Regulation of RNA biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0219941188 | 0.9291416474 | 0.3553758134 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2808130203 |
| GSE13712_SHEAR | Up | 0.4687272454 |
| GSE13712_STATIC | Up | 0.3861848004 |
| GSE19018 | Down | -0.2673531271 |
| GSE19899_A1 | Down | -0.0160158726 |
| GSE19899_A2 | Up | 0.3736151412 |
| PubMed_21979375_A1 | Up | 0.4941444410 |
| PubMed_21979375_A2 | Up | 0.3362142335 |
| GSE35957 | Down | -0.1491221647 |
| GSE36640 | Down | -0.0262710298 |
| GSE54402 | Up | 0.0669450124 |
| GSE9593 | Up | 0.5030083535 |
| GSE43922 | Down | -0.1951574413 |
| GSE24585 | Up | 0.4632372339 |
| GSE37065 | Up | 0.3181907904 |
| GSE28863_A1 | Up | 0.7704150283 |
| GSE28863_A2 | Up | 1.0908354637 |
| GSE28863_A3 | Down | -0.2000589525 |
| GSE28863_A4 | Up | 0.0507542909 |
| GSE48662 | Up | 0.0520472006 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022249 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037080 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
