HCSGD entry for ZP3

1. General information

Official gene symbolZP3
Entrez ID7784
Gene full namezona pellucida glycoprotein 3 (sperm receptor)
Other gene symbolsZP3A ZP3B ZPC Zp-3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001669Acrosomal vesicleISScellular_component
GO:0001809Positive regulation of type IV hypersensitivityISSbiological_process
GO:0001825Blastocyst formationISSbiological_process
GO:0002081Outer acrosomal membraneISScellular_component
GO:0002455Humoral immune response mediated by circulating immunoglobulinISSbiological_process
GO:0002687Positive regulation of leukocyte migrationISSbiological_process
GO:0002922Positive regulation of humoral immune responseIDAbiological_process
GO:0004871Signal transducer activityIMPmolecular_function
GO:0005384Manganese ion transmembrane transporter activityISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEA TAScellular_component
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceIMPcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005771Multivesicular bodyISScellular_component
GO:0005783Endoplasmic reticulumISScellular_component
GO:0005794Golgi apparatusISScellular_component
GO:0005886Plasma membraneISScellular_component
GO:0006828Manganese ion transportISSbiological_process
GO:0006886Intracellular protein transportISSbiological_process
GO:0007338Single fertilizationTASbiological_process
GO:0007339Binding of sperm to zona pellucidaIDA IGI IMP TASbiological_process
GO:0010513Positive regulation of phosphatidylinositol biosynthetic processISSbiological_process
GO:0015279Store-operated calcium channel activityIDAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030141Secretory granuleISScellular_component
GO:0030246Carbohydrate bindingIDAmolecular_function
GO:0031012Extracellular matrixIDAcellular_component
GO:0032190Acrosin bindingIPImolecular_function
GO:0032504Multicellular organism reproductionTASbiological_process
GO:0032729Positive regulation of interferon-gamma productionISSbiological_process
GO:0032753Positive regulation of interleukin-4 productionISSbiological_process
GO:0034220Ion transmembrane transportIDA ISSbiological_process
GO:0035556Intracellular signal transductionIMPbiological_process
GO:0035803Egg coat formationISSbiological_process
GO:0042102Positive regulation of T cell proliferationISSbiological_process
GO:0045860Positive regulation of protein kinase activityIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedISSbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0048015Phosphatidylinositol-mediated signalingISSbiological_process
GO:0048471Perinuclear region of cytoplasmISScellular_component
GO:0048599Oocyte developmentISSbiological_process
GO:0050729Positive regulation of inflammatory responseISSbiological_process
GO:0051897Positive regulation of protein kinase B signalingISSbiological_process
GO:0055085Transmembrane transportIDA ISSbiological_process
GO:0070528Protein kinase C signalingIMPbiological_process
GO:0070588Calcium ion transmembrane transportIDAbiological_process
GO:0071421Manganese ion transmembrane transportISSbiological_process
GO:0072511Divalent inorganic cation transportIDAbiological_process
GO:0090280Positive regulation of calcium ion importIDAbiological_process
GO:2000344Positive regulation of acrosome reactionIDAbiological_process
GO:2000360Negative regulation of binding of sperm to zona pellucidaIDAbiological_process
GO:2000368Positive regulation of acrosomal vesicle exocytosisIDA IMPbiological_process
GO:2000386Positive regulation of ovarian follicle developmentISSbiological_process
GO:2000388Positive regulation of antral ovarian follicle growthISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74576927930.91513820900.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Down-0.0767528846
GSE24585Down-0.1292261405
GSE37065Down-0.0035236367
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.1815013767

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-7-5pMIMAT0000252MIRT025811MicroarrayFunctional MTI (Weak)19073608
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.