HCSGD entry for TSEN34
1. General information
| Official gene symbol | TSEN34 |
|---|---|
| Entrez ID | 79042 |
| Gene full name | tRNA splicing endonuclease 34 homolog (S. cerevisiae) |
| Other gene symbols | LENG5 PCH2C SEN34 SEN34L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000213 | TRNA-intron endonuclease activity | IEA | molecular_function |
| GO:0000214 | TRNA-intron endonuclease complex | IEA | cellular_component |
| GO:0000379 | TRNA-type intron splice site recognition and cleavage | IEA | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006388 | TRNA splicing, via endonucleolytic cleavage and ligation | IEA | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0159931917 | 0.9930410129 | 0.3125143281 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1862828110 |
| GSE13712_SHEAR | Up | 0.0676902779 |
| GSE13712_STATIC | Up | 0.2334289152 |
| GSE19018 | Up | 0.3406385582 |
| GSE19899_A1 | Up | 0.4302472370 |
| GSE19899_A2 | Up | 1.1023768170 |
| PubMed_21979375_A1 | Up | 1.1783522454 |
| PubMed_21979375_A2 | Up | 0.4691642689 |
| GSE35957 | Up | 0.1650575684 |
| GSE36640 | Up | 0.4586138797 |
| GSE54402 | Up | 0.6935587240 |
| GSE9593 | Up | 0.1900815975 |
| GSE43922 | Up | 0.0974672879 |
| GSE24585 | Up | 0.0724822786 |
| GSE37065 | Down | -0.1449273650 |
| GSE28863_A1 | Down | -0.0193147240 |
| GSE28863_A2 | Up | 0.0319781560 |
| GSE28863_A3 | Down | -0.0465741750 |
| GSE28863_A4 | Up | 0.0894006522 |
| GSE48662 | Up | 0.3390583111 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025748 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029248 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041464 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048138 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
