HCSGD entry for TRPM8

1. General information

Official gene symbolTRPM8
Entrez ID79054
Gene full nametransient receptor potential cation channel, subfamily M, member 8
Other gene symbolsLTRPC6 TRPP8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005216Ion channel activityIEAmolecular_function
GO:0005262Calcium channel activityIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0006874Cellular calcium ion homeostasisIEAbiological_process
GO:0009409Response to coldIEAbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0045121Membrane raftIEAcellular_component
GO:0050955ThermoceptionIEAbiological_process
GO:0051289Protein homotetramerizationIEAbiological_process
GO:0070207Protein homotrimerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10124105470.98577215910.66238274921.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1982200577
GSE13712_SHEARUp0.0947897972
GSE13712_STATICUp0.0478194304
GSE19018Up0.0976901685
GSE19899_A1Up0.0853914579
GSE19899_A2Up0.4041063056
PubMed_21979375_A1Down-0.0258968520
PubMed_21979375_A2Up0.8224789795
GSE35957Up0.1381742404
GSE36640Up0.1303766895
GSE54402Up0.6090220003
GSE9593Up0.0212504068
GSE43922Up0.2729958943
GSE24585Up0.0198018917
GSE37065Up0.0583314723
GSE28863_A1Up0.0195304304
GSE28863_A2Up0.0978324413
GSE28863_A3Up0.1107022799
GSE28863_A4Down-0.0119144489
GSE48662Up0.0222788265

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018725MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.