HCSGD entry for ALG12


1. General information

Official gene symbolALG12
Entrez ID79087
Gene full nameALG12, alpha-1,6-mannosyltransferase
Other gene symbolsCDG1G ECM39 PP14673 hALG12
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000009Alpha-1,6-mannosyltransferase activityICmolecular_function
GO:0005783Endoplasmic reticulumNAScellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006457Protein foldingNASbiological_process
GO:0006487Protein N-linked glycosylationIGIbiological_process
GO:0006488Dolichol-linked oligosaccharide biosynthetic processIDA TASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016757Transferase activity, transferring glycosyl groupsIEAmolecular_function
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0052917Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activityIEAmolecular_function
GO:0097502MannosylationICbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31820749590.70126919570.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0145305600
GSE13712_SHEARDown-0.2475791477
GSE13712_STATICDown-0.2258183764
GSE19018Up0.2175530455
GSE19899_A1Down-0.1598821545
GSE19899_A2Up0.4348473296
PubMed_21979375_A1Up0.2515587680
PubMed_21979375_A2Up0.4577499728
GSE35957Down-0.4006972393
GSE36640Up0.0185791871
GSE54402Up0.1263046133
GSE9593Up0.0321922421
GSE43922Up0.0500086082
GSE24585Down-0.0637149687
GSE37065Down-0.1691036204
GSE28863_A1Up0.2706271068
GSE28863_A2Up0.4327814304
GSE28863_A3Down-0.0943586507
GSE28863_A4Down-0.1571358214
GSE48662Up0.2815773181

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017824MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.