HCSGD entry for USB1
1. General information
| Official gene symbol | USB1 |
|---|---|
| Entrez ID | 79650 |
| Gene full name | U6 snRNA biogenesis 1 |
| Other gene symbols | C16orf57 HVSL1 Mpn1 PN hUsb1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000175 | 3'-5'-exoribonuclease activity | IDA | molecular_function |
| GO:0004518 | Nuclease activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA IMP | biological_process |
| GO:0034477 | U6 snRNA 3'-end processing | IEA IMP | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | IDA | biological_process |
| GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0299489191 | 0.8626416474 | 0.4005515752 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3296390510 |
| GSE13712_SHEAR | Up | 0.1545221039 |
| GSE13712_STATIC | Up | 0.2840931561 |
| GSE19018 | Down | -0.1494960650 |
| GSE19899_A1 | Up | 0.0953064808 |
| GSE19899_A2 | Up | 0.8584555838 |
| PubMed_21979375_A1 | Up | 1.5722847336 |
| PubMed_21979375_A2 | Up | 1.2762560758 |
| GSE35957 | Up | 0.1361862445 |
| GSE36640 | Up | 0.1071094948 |
| GSE54402 | Up | 0.6318938768 |
| GSE9593 | Down | -0.0612405435 |
| GSE43922 | Up | 0.5469997925 |
| GSE24585 | Down | -0.0571729232 |
| GSE37065 | Down | -0.0366219846 |
| GSE28863_A1 | Down | -0.4346335469 |
| GSE28863_A2 | Down | -0.0812472817 |
| GSE28863_A3 | Up | 0.0476587160 |
| GSE28863_A4 | Up | 0.0318631908 |
| GSE48662 | Down | -0.2591609549 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028794 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050173 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
