HCSGD entry for NLRX1

1. General information

Official gene symbolNLRX1
Entrez ID79671
Gene full nameNLR family member X1
Other gene symbolsCLR11.3 DLNB26 NOD26 NOD5 NOD9
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0005741Mitochondrial outer membraneTAScellular_component
GO:0016032Viral processIEAbiological_process
GO:0032480Negative regulation of type I interferon productionTASbiological_process
GO:0032688Negative regulation of interferon-beta productionIEAbiological_process
GO:0032715Negative regulation of interleukin-6 productionIEAbiological_process
GO:0039536Negative regulation of RIG-I signaling pathwayIEAbiological_process
GO:0043124Negative regulation of I-kappaB kinase/NF-kappaB signalingIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045824Negative regulation of innate immune responseIEAbiological_process
GO:0050728Negative regulation of inflammatory responseIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.42764550360.45674396870.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2428143970
GSE13712_SHEARUp0.4313069042
GSE13712_STATICUp0.3784476369
GSE19018Down-0.0658635048
GSE19899_A1Down-0.2506491423
GSE19899_A2Up0.1506597380
PubMed_21979375_A1Up0.1092743236
PubMed_21979375_A2Up0.4213564357
GSE35957Up0.2577995837
GSE36640Up0.3709831333
GSE54402Down-0.3947604995
GSE9593Up0.1689394539
GSE43922Up0.0487650581
GSE24585Up0.0818061531
GSE37065Down-0.2536117286
GSE28863_A1Down-0.0156724164
GSE28863_A2Down-0.0565405147
GSE28863_A3Down-0.0155039582
GSE28863_A4Down-0.0615861803
GSE48662Down-0.0281347825

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022772MicroarrayFunctional MTI (Weak)18668037
hsa-miR-331-3pMIMAT0000760MIRT043504CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.