HCSGD entry for FZD3

1. General information

Official gene symbolFZD3
Entrez ID7976
Gene full namefrizzled family receptor 3
Other gene symbolsFz-3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001736Establishment of planar polarityIBA IEAbiological_process
GO:0001764Neuron migrationIEAbiological_process
GO:0001843Neural tube closureIBA IEAbiological_process
GO:0001942Hair follicle developmentIEAbiological_process
GO:0001944Vasculature developmentIBAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007199G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerIBAbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0016324Apical plasma membraneIEAcellular_component
GO:0016328Lateral plasma membraneIEAcellular_component
GO:0017147Wnt-protein bindingIPImolecular_function
GO:0021754Facial nucleus developmentIBAbiological_process
GO:0030165PDZ domain bindingIPImolecular_function
GO:0030182Neuron differentiationISSbiological_process
GO:0030424AxonIBA IEAcellular_component
GO:0030425DendriteIBA IEAcellular_component
GO:0032589Neuron projection membraneIBAcellular_component
GO:0033278Cell proliferation in midbrainIBA IEAbiological_process
GO:0036342Post-anal tail morphogenesisIEAbiological_process
GO:0042472Inner ear morphogenesisIBA IEAbiological_process
GO:0042813Wnt-activated receptor activityIBA IC IEAmolecular_function
GO:0043025Neuronal cell bodyIBA IEAcellular_component
GO:0045177Apical part of cellIBAcellular_component
GO:0048786Presynaptic active zoneIBA IEAcellular_component
GO:0060070Canonical Wnt signaling pathwayIDAbiological_process
GO:0071679Commissural neuron axon guidanceIBA IEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15594749060.26913823180.78453629590.9928503714

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0289292745
GSE13712_SHEARDown-0.2312411167
GSE13712_STATICUp0.3001235880
GSE19018Up0.1024750420
GSE19899_A1Up0.0669283173
GSE19899_A2Up0.3283391204
PubMed_21979375_A1Up0.2354482789
PubMed_21979375_A2Up0.4458909755
GSE35957Down-0.3714327909
GSE36640Up0.0632352088
GSE54402Up0.0882161430
GSE9593Down-0.2525873644
GSE43922Up0.4826000714
GSE24585Down-0.0228272432
GSE37065Up0.1685620095
GSE28863_A1Down-0.4479531245
GSE28863_A2Down-0.1541548006
GSE28863_A3Up0.5208591196
GSE28863_A4Down-0.5972134962
GSE48662Up0.1109877398

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-31-5pMIMAT0000089MIRT004984Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI19524507
hsa-miR-98-5pMIMAT0000096MIRT027778MicroarrayFunctional MTI (Weak)19088304
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.