HCSGD entry for HSD3B7
1. General information
| Official gene symbol | HSD3B7 |
|---|---|
| Entrez ID | 80270 |
| Gene full name | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 |
| Other gene symbols | CBAS1 PFIC4 SDR11E3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity | IEA NAS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006694 | Steroid biosynthetic process | IEA | biological_process |
| GO:0006699 | Bile acid biosynthetic process | TAS | biological_process |
| GO:0008206 | Bile acid metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047016 | Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2743870218 | 0.1077077543 | 0.9705544404 | 0.6279048283 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1258042792 |
| GSE13712_SHEAR | Down | -0.1654426963 |
| GSE13712_STATIC | Down | -0.2290303330 |
| GSE19018 | Down | -0.2955446582 |
| GSE19899_A1 | Down | -0.3563881140 |
| GSE19899_A2 | Down | -0.5756504134 |
| PubMed_21979375_A1 | Up | 0.1898438065 |
| PubMed_21979375_A2 | Up | 0.4133542997 |
| GSE35957 | Down | -0.2451150947 |
| GSE36640 | Up | 0.5657722715 |
| GSE54402 | Down | -0.4431693158 |
| GSE9593 | Up | 0.4330315152 |
| GSE43922 | Down | -0.3118205438 |
| GSE24585 | Down | -0.0136402639 |
| GSE37065 | Up | 0.0632271372 |
| GSE28863_A1 | Up | 0.0450863950 |
| GSE28863_A2 | Up | 1.1308602491 |
| GSE28863_A3 | Down | -0.3735354197 |
| GSE28863_A4 | Up | 0.1097201350 |
| GSE48662 | Up | 0.1509557459 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018942 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1 | MIMAT0000416 | MIRT024008 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
