HCSGD entry for SLC38A1
1. General information
| Official gene symbol | SLC38A1 |
|---|---|
| Entrez ID | 81539 |
| Gene full name | solute carrier family 38, member 1 |
| Other gene symbols | ATA1 NAT2 SAT1 SNAT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001504 | Neurotransmitter uptake | TAS | biological_process |
| GO:0003333 | Amino acid transmembrane transport | NAS | biological_process |
| GO:0005283 | Sodium:amino acid symporter activity | NAS | molecular_function |
| GO:0005886 | Plasma membrane | IEA TAS | cellular_component |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006865 | Amino acid transport | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0015175 | Neutral amino acid transmembrane transporter activity | NAS | molecular_function |
| GO:0015186 | L-glutamine transmembrane transporter activity | IEA | molecular_function |
| GO:0015804 | Neutral amino acid transport | NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA NAS | cellular_component |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | NAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | NAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4924911060 | 0.0718942593 | 0.9999902473 | 0.5049092800 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2843547271 |
| GSE13712_SHEAR | Up | 0.5752309489 |
| GSE13712_STATIC | Up | 0.2873411962 |
| GSE19018 | Down | -0.0899341625 |
| GSE19899_A1 | Down | -0.2701298357 |
| GSE19899_A2 | Down | -0.0198336381 |
| PubMed_21979375_A1 | Down | -0.3818761381 |
| PubMed_21979375_A2 | Up | 0.1206501878 |
| GSE35957 | Up | 0.9934607455 |
| GSE36640 | Up | 0.1955770757 |
| GSE54402 | Down | -0.9295480391 |
| GSE9593 | Down | -0.0957783555 |
| GSE43922 | Up | 0.0324656376 |
| GSE24585 | Down | -0.1748089921 |
| GSE37065 | Down | -0.4793278088 |
| GSE28863_A1 | Down | -0.0378840700 |
| GSE28863_A2 | Down | -0.3327084942 |
| GSE28863_A3 | Down | -0.4469515562 |
| GSE28863_A4 | Up | 0.0992554902 |
| GSE48662 | Down | -0.0163292940 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001414 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT001576 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005141 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT024213 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-320d | MIMAT0006764 | MIRT035811 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037169 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041800 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-758-3p | MIMAT0003879 | NA | hsa-miR-758 | 21885853 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
