HCSGD entry for CAMK2B

1. General information

Official gene symbolCAMK2B
Entrez ID816
Gene full namecalcium/calmodulin-dependent protein kinase II beta
Other gene symbolsCAM2 CAMK2 CAMKB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleIEAbiological_process
GO:0002030Inhibitory G-protein coupled receptor phosphorylationIEAbiological_process
GO:0003779Actin bindingIEAmolecular_function
GO:0004672Protein kinase activityIEAmolecular_function
GO:0004674Protein serine/threonine kinase activityIEAmolecular_function
GO:0004683Calmodulin-dependent protein kinase activityIEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005815Microtubule organizing centerIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0006816Calcium ion transportIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0010976Positive regulation of neuron projection developmentISSbiological_process
GO:0014733Regulation of skeletal muscle adaptationTASbiological_process
GO:0018105Peptidyl-serine phosphorylationIEAbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0032222Regulation of synaptic transmission, cholinergicIEAbiological_process
GO:0033017Sarcoplasmic reticulum membraneIEAcellular_component
GO:0046686Response to cadmium ionIEAbiological_process
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0048169Regulation of long-term neuronal synaptic plasticityTASbiological_process
GO:0050885Neuromuscular process controlling balanceIEAbiological_process
GO:0051233Spindle midzoneIEAcellular_component
GO:0051823Regulation of synapse structural plasticityTASbiological_process
GO:0051924Regulation of calcium ion transportTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0060466Activation of meiosis involved in egg activationIEAbiological_process
GO:0060998Regulation of dendritic spine developmentTASbiological_process
GO:0061003Positive regulation of dendritic spine morphogenesisISSbiological_process
GO:0090129Positive regulation of synapse maturationISSbiological_process
GO:2001235Positive regulation of apoptotic signaling pathwayIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66796030930.84133192130.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1375398857
GSE13712_SHEARUp0.0014021799
GSE13712_STATICDown-0.1409251858
GSE19018Up0.0053295428
GSE19899_A1Down-0.0035801034
GSE19899_A2Up0.1355987784
PubMed_21979375_A1Down-0.0515972729
PubMed_21979375_A2Up0.0489102932
GSE35957Up0.1364883887
GSE36640Up0.1423864607
GSE54402Up0.0931789100
GSE9593Up0.0298570620
GSE43922Up0.0231708843
GSE24585Down-0.4336794971
GSE37065Down-0.0773505909
GSE28863_A1Down-0.0831188839
GSE28863_A2Up0.0707622717
GSE28863_A3Up0.3233101767
GSE28863_A4Up0.0966592279
GSE48662Up0.0623106823

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrileDB07168 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT045124CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.