HCSGD entry for CAMK2D

1. General information

Official gene symbolCAMK2D
Entrez ID817
Gene full namecalcium/calmodulin-dependent protein kinase II delta
Other gene symbolsCAMKD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleIEAbiological_process
GO:0001558Regulation of cell growthNASbiological_process
GO:0002026Regulation of the force of heart contractionTASbiological_process
GO:0002028Regulation of sodium ion transportIEAbiological_process
GO:0004683Calmodulin-dependent protein kinase activityIDA IEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusISScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmISScellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005954Calcium- and calmodulin-dependent protein kinase complexTAScellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006468Protein phosphorylationIDAbiological_process
GO:0006816Calcium ion transportIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008016Regulation of heart contractionTASbiological_process
GO:0010613Positive regulation of cardiac muscle hypertrophyIMPbiological_process
GO:0010881Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionTASbiological_process
GO:0014704Intercalated discIEAcellular_component
GO:0018105Peptidyl-serine phosphorylationIDAbiological_process
GO:0018107Peptidyl-threonine phosphorylationIDAbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0030315T-tubuleIEAcellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0031432Titin bindingIPImolecular_function
GO:0031594Neuromuscular junctionIEAcellular_component
GO:0033017Sarcoplasmic reticulum membraneIEAcellular_component
GO:0034704Calcium channel complexISScellular_component
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043194Axon initial segmentIEAcellular_component
GO:0044325Ion channel bindingISSmolecular_function
GO:0046777Protein autophosphorylationIEAbiological_process
GO:0055119Relaxation of cardiac muscleISSbiological_process
GO:0060314Regulation of ryanodine-sensitive calcium-release channel activityTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0060341Regulation of cellular localizationIMPbiological_process
GO:0071277Cellular response to calcium ionTASbiological_process
GO:0086003Cardiac muscle cell contractionISSbiological_process
GO:1901725Regulation of histone deacetylase activityTASbiological_process
GO:1901897Regulation of relaxation of cardiac muscleIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87206975040.00643651080.99999024730.1635283784

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1478832148
GSE13712_SHEARDown-0.4064885620
GSE13712_STATICDown-0.2543833575
GSE19018Up0.0272360770
GSE19899_A1Down-1.5636168400
GSE19899_A2Down-1.6022241538
PubMed_21979375_A1Down-2.1178104585
PubMed_21979375_A2Down-1.1991344378
GSE35957Up0.5583599909
GSE36640Up0.1595805551
GSE54402Down-1.0748583994
GSE9593Up0.8621475249
GSE43922Down-1.0205141389
GSE24585Down-0.1543171180
GSE37065Up0.1434077156
GSE28863_A1Up0.0835644800
GSE28863_A2Down-0.0914491290
GSE28863_A3Down-0.5051957911
GSE28863_A4Down-0.1100552266
GSE48662Up0.3929250500

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILEDB07853 -
(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDEDB08039 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-7-5pMIMAT0000252MIRT025927MicroarrayFunctional MTI (Weak)19073608
hsa-miR-484MIMAT0002174MIRT041998CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052455CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.