HCSGD entry for DOCK8

1. General information

Official gene symbolDOCK8
Entrez ID81704
Gene full namededicator of cytokinesis 8
Other gene symbolsMRD2 ZIR8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005085Guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.79468342770.80197469320.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0755073019
GSE13712_SHEARDown-0.0507002270
GSE13712_STATICDown-0.2392322565
GSE19018Down-0.0305247966
GSE19899_A1Up0.0356376050
GSE19899_A2Up0.0830533276
PubMed_21979375_A1Down-0.0790844323
PubMed_21979375_A2Down-0.0430555400
GSE35957Up0.0806366041
GSE36640Up0.0209999484
GSE54402Up0.1498739637
GSE9593Up0.0215556974
GSE43922Down-0.0133252395
GSE24585Up0.3468515057
GSE37065Up0.0157561470
GSE28863_A1Down-0.1982653013
GSE28863_A2Down-0.1099767191
GSE28863_A3Up0.1466906647
GSE28863_A4Up0.0939665790
GSE48662Down-0.0183967612

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.