HCSGD entry for ELL

1. General information

Official gene symbolELL
Entrez ID8178
Gene full nameelongation factor RNA polymerase II
Other gene symbolsC19orf17 ELL1 MEN PPP1R68
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001701In utero embryonic developmentIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterIEA TASbiological_process
GO:0008023Transcription elongation factor complexIEAcellular_component
GO:0010467Gene expressionTASbiological_process
GO:0010923Negative regulation of phosphatase activityIDAbiological_process
GO:0015030Cajal bodyIEAcellular_component
GO:0016032Viral processTASbiological_process
GO:0016607Nuclear speckIDAcellular_component
GO:0019902Phosphatase bindingIDAmolecular_function
GO:0032786Positive regulation of DNA-templated transcription, elongationTASbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04241735120.99163999090.46020902721.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0328714285
GSE13712_SHEARUp0.1754008278
GSE13712_STATICUp0.2399318948
GSE19018Down-0.0225470119
GSE19899_A1Up0.1576770767
GSE19899_A2Up0.6788684403
PubMed_21979375_A1Up0.5294943167
PubMed_21979375_A2Up0.6429373652
GSE35957Up0.2151309729
GSE36640Down-0.0822288171
GSE54402Up0.6090210904
GSE9593Up0.0819610105
GSE43922Up0.4321333973
GSE24585Up0.1876867471
GSE37065Up0.0671021372
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0048870932

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-769-3pMIMAT0003887MIRT039101CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.