HCSGD entry for ADAMTS12
1. General information
| Official gene symbol | ADAMTS12 |
|---|---|
| Entrez ID | 81792 |
| Gene full name | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| Other gene symbols | PRO4389 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0083698188 | 0.4803227689 | 0.2368838710 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9519536484 |
| GSE13712_SHEAR | Down | -0.0446438731 |
| GSE13712_STATIC | Down | -0.0725205226 |
| GSE19018 | Up | 0.5866597840 |
| GSE19899_A1 | Up | 0.1198611598 |
| GSE19899_A2 | Up | 0.2617678470 |
| PubMed_21979375_A1 | Down | -0.7066847232 |
| PubMed_21979375_A2 | Up | 0.4523287711 |
| GSE35957 | Up | 0.6812174154 |
| GSE36640 | Up | 2.4366108603 |
| GSE54402 | Up | 0.1413412263 |
| GSE9593 | Up | 0.1540317663 |
| GSE43922 | Down | -0.1225826140 |
| GSE24585 | Up | 0.0708224812 |
| GSE37065 | Down | -0.8981747610 |
| GSE28863_A1 | Up | 0.8580426028 |
| GSE28863_A2 | Up | 1.2929244928 |
| GSE28863_A3 | Up | 0.3885396971 |
| GSE28863_A4 | Up | 0.0692378504 |
| GSE48662 | Up | 0.5596795744 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018249 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029674 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
