HCSGD entry for CHAF1B
1. General information
| Official gene symbol | CHAF1B |
|---|---|
| Entrez ID | 8208 |
| Gene full name | chromatin assembly factor 1, subunit B (p60) |
| Other gene symbols | CAF-1 CAF-IP60 CAF1 CAF1A CAF1P60 MPHOSPH7 MPP7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003682 | Chromatin binding | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA NAS | cellular_component |
| GO:0005654 | Nucleoplasm | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006260 | DNA replication | IEA | biological_process |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006335 | DNA replication-dependent nucleosome assembly | TAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0031497 | Chromatin assembly | IDA | biological_process |
| GO:0033186 | CAF-1 complex | IDA | cellular_component |
| GO:0042393 | Histone binding | NAS | molecular_function |
| GO:0051082 | Unfolded protein binding | TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9501174613 | 0.0034161278 | 0.9999902473 | 0.1187695652 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1281362331 |
| GSE13712_SHEAR | Down | -0.0814191366 |
| GSE13712_STATIC | Up | 0.2377880871 |
| GSE19018 | Up | 0.0011539934 |
| GSE19899_A1 | Down | -0.2865727630 |
| GSE19899_A2 | Down | -0.9610593363 |
| PubMed_21979375_A1 | Down | -1.6588917163 |
| PubMed_21979375_A2 | Down | -1.3776537180 |
| GSE35957 | Down | -0.5184265657 |
| GSE36640 | Down | -3.4767457601 |
| GSE54402 | Down | -0.2792042852 |
| GSE9593 | Down | -0.4546222107 |
| GSE43922 | Down | -1.6220649115 |
| GSE24585 | Up | 0.2146435632 |
| GSE37065 | Down | -0.3991781687 |
| GSE28863_A1 | Up | 0.0248668781 |
| GSE28863_A2 | Up | 0.2166766752 |
| GSE28863_A3 | Up | 0.2070836066 |
| GSE28863_A4 | Up | 0.1589842096 |
| GSE48662 | Down | -1.2823873563 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016399 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020576 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023664 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042223 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
