HCSGD entry for CAPZA1
1. General information
| Official gene symbol | CAPZA1 |
|---|---|
| Entrez ID | 829 |
| Gene full name | capping protein (actin filament) muscle Z-line, alpha 1 |
| Other gene symbols | CAPPA1 CAPZ CAZ1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | TAS | cellular_component |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008290 | F-actin capping protein complex | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | TAS | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0051693 | Actin filament capping | IEA | biological_process |
| GO:0071203 | WASH complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4443507504 | 0.9078010068 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0967131733 |
| GSE13712_SHEAR | Up | 0.0534393131 |
| GSE13712_STATIC | Up | 0.0395002907 |
| GSE19018 | Up | 0.0593787594 |
| GSE19899_A1 | Up | 0.0941333239 |
| GSE19899_A2 | Down | -0.0799662947 |
| PubMed_21979375_A1 | Up | 0.0755319473 |
| PubMed_21979375_A2 | Up | 0.1279998375 |
| GSE35957 | Up | 0.0022384607 |
| GSE36640 | Up | 0.3250736077 |
| GSE54402 | Up | 0.2637681462 |
| GSE9593 | Down | -0.1248537337 |
| GSE43922 | Down | -0.0385931246 |
| GSE24585 | Up | 0.2106967519 |
| GSE37065 | Up | 0.1366111983 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.3279581014 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT004060 | Microarray//Microarray;Other | Functional MTI (Weak) | 19073608 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT004060 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021466 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-140-3p | MIMAT0004597 | MIRT021670 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047861 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
