HCSGD entry for PCBD2
1. General information
| Official gene symbol | PCBD2 |
|---|---|
| Entrez ID | 84105 |
| Gene full name | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 |
| Other gene symbols | DCOH2 DCOHM PHS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004505 | Phenylalanine 4-monooxygenase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006729 | Tetrahydrobiopterin biosynthetic process | IEA | biological_process |
| GO:0008124 | 4-alpha-hydroxytetrahydrobiopterin dehydratase activity | IEA | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0051289 | Protein homotetramerization | IEA | biological_process |
| GO:0051291 | Protein heterooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1299793359 | 0.7950523802 | 0.7321177188 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1834780552 |
| GSE13712_SHEAR | Up | 0.1903739694 |
| GSE13712_STATIC | Up | 0.1604558434 |
| GSE19018 | Down | -0.0358623336 |
| GSE19899_A1 | Down | -0.0407243186 |
| GSE19899_A2 | Up | 0.7072222374 |
| PubMed_21979375_A1 | Up | 0.2563479689 |
| PubMed_21979375_A2 | Up | 0.4749529267 |
| GSE35957 | Down | -0.1054266799 |
| GSE36640 | Up | 0.2092611138 |
| GSE54402 | Down | -0.2024638610 |
| GSE9593 | Down | -0.4768951876 |
| GSE43922 | Up | 0.1855602636 |
| GSE24585 | Up | 0.6278561855 |
| GSE37065 | Up | 0.0293128473 |
| GSE28863_A1 | Up | 0.2920192507 |
| GSE28863_A2 | Up | 0.3231675381 |
| GSE28863_A3 | Down | -0.2910076473 |
| GSE28863_A4 | Down | -0.1141799139 |
| GSE48662 | Down | -0.3420496245 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
