HCSGD entry for RNF135
1. General information
| Official gene symbol | RNF135 |
|---|---|
| Entrez ID | 84282 |
| Gene full name | ring finger protein 135 |
| Other gene symbols | MMFD REUL Riplet |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0032480 | Negative regulation of type I interferon production | TAS | biological_process |
| GO:0032728 | Positive regulation of interferon-beta production | IMP | biological_process |
| GO:0043021 | Ribonucleoprotein complex binding | IPI | molecular_function |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045088 | Regulation of innate immune response | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1429549751 | 0.5654537594 | 0.7573908816 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3084211623 |
| GSE13712_SHEAR | Down | -0.3093899057 |
| GSE13712_STATIC | Up | 0.0212713513 |
| GSE19018 | Up | 0.4144464535 |
| GSE19899_A1 | Down | -0.3608045829 |
| GSE19899_A2 | Up | 0.7403667958 |
| PubMed_21979375_A1 | Up | 0.5328096229 |
| PubMed_21979375_A2 | Up | 0.8756820436 |
| GSE35957 | Up | 0.0171775102 |
| GSE36640 | Up | 0.7087218096 |
| GSE54402 | Down | -0.1509077554 |
| GSE9593 | Up | 0.2890183291 |
| GSE43922 | Down | -0.0668285786 |
| GSE24585 | Down | -0.0924982219 |
| GSE37065 | Down | -0.0031404395 |
| GSE28863_A1 | Down | -0.0655066725 |
| GSE28863_A2 | Down | -0.1386683679 |
| GSE28863_A3 | Down | -0.4483799870 |
| GSE28863_A4 | Down | -0.0071789188 |
| GSE48662 | Up | 0.1445534369 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
