HCSGD entry for LZTS2
1. General information
| Official gene symbol | LZTS2 |
|---|---|
| Entrez ID | 84445 |
| Gene full name | leucine zipper, putative tumor suppressor 2 |
| Other gene symbols | LAPSER1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000910 | Cytokinesis | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005813 | Centrosome | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0030178 | Negative regulation of Wnt signaling pathway | IEA | biological_process |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0051013 | Microtubule severing | IEA | biological_process |
| GO:0051168 | Nuclear export | IEA | biological_process |
| GO:0051255 | Spindle midzone assembly | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4833810873 | 0.4032135519 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0035661204 |
| GSE13712_SHEAR | Up | 0.3711572143 |
| GSE13712_STATIC | Up | 0.0749151930 |
| GSE19018 | Down | -0.1016905160 |
| GSE19899_A1 | Down | -0.5778290572 |
| GSE19899_A2 | Up | 0.0462640991 |
| PubMed_21979375_A1 | Up | 0.1148821971 |
| PubMed_21979375_A2 | Up | 0.4860312096 |
| GSE35957 | Down | -0.0402684844 |
| GSE36640 | Up | 0.1146997927 |
| GSE54402 | Down | -0.1786271721 |
| GSE9593 | Up | 0.4803925664 |
| GSE43922 | Down | -0.0810693458 |
| GSE24585 | Down | -0.1134241274 |
| GSE37065 | Down | -0.0113729523 |
| GSE28863_A1 | Down | -0.0247097199 |
| GSE28863_A2 | Up | 0.0329819891 |
| GSE28863_A3 | Down | -0.3858344054 |
| GSE28863_A4 | Down | -0.0506090840 |
| GSE48662 | Up | 0.6217326949 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017535 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
