HCSGD entry for SPIRE2

1. General information

Official gene symbolSPIRE2
Entrez ID84501
Gene full namespire homolog 2 (Drosophila)
Other gene symbolsSpir-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0005829CytosolIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0005938Cell cortexISScellular_component
GO:0015031Protein transportIEAbiological_process
GO:0016192Vesicle-mediated transportISSbiological_process
GO:0030036Actin cytoskeleton organizationIMPbiological_process
GO:0030659Cytoplasmic vesicle membraneISScellular_component
GO:0032154Cleavage furrowISScellular_component
GO:0036089Cleavage furrow formationISSbiological_process
GO:0040038Polar body extrusion after meiotic divisionsISSbiological_process
GO:0046907Intracellular transportISSbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0051295Establishment of meiotic spindle localizationIMPbiological_process
GO:0070649Formin-nucleated actin cable assemblyISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78851681550.54400964250.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0288747703
GSE13712_SHEARUp0.0558897853
GSE13712_STATICUp0.0596231866
GSE19018Down-0.0746063092
GSE19899_A1Down-0.0653617293
GSE19899_A2Up0.0032261344
PubMed_21979375_A1Down-0.3742964316
PubMed_21979375_A2Up0.0129636690
GSE35957Up0.0331189597
GSE36640Up0.0334426241
GSE54402Down-0.2109521057
GSE9593Down-0.0228235133
GSE43922Up0.0523688689
GSE24585Up0.2946172613
GSE37065Down-0.0691264101
GSE28863_A1Down-0.0591537794
GSE28863_A2Down-0.3064304107
GSE28863_A3Up0.2336599461
GSE28863_A4Up0.1959215209
GSE48662Down-0.1212973307

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

LATRUNCULIN BDB08080 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.