HCSGD entry for PSRC1
1. General information
| Official gene symbol | PSRC1 |
|---|---|
| Entrez ID | 84722 |
| Gene full name | proline/serine-rich coiled-coil 1 |
| Other gene symbols | DDA3 FP3214 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000922 | Spindle pole | IDA | cellular_component |
| GO:0001578 | Microtubule bundle formation | IEA ISS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0005819 | Spindle | IEA ISS | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005876 | Spindle microtubule | IDA | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007080 | Mitotic metaphase plate congression | IDA | biological_process |
| GO:0008017 | Microtubule binding | IEA ISS | molecular_function |
| GO:0015630 | Microtubule cytoskeleton | ISS | cellular_component |
| GO:0030308 | Negative regulation of cell growth | IEA ISS | biological_process |
| GO:0030496 | Midbody | IEA ISS | cellular_component |
| GO:0031116 | Positive regulation of microtubule polymerization | IEA ISS | biological_process |
| GO:0045737 | Positive regulation of cyclin-dependent protein kinase activity | ISS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IEA ISS | biological_process |
| GO:0060236 | Regulation of mitotic spindle organization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9982122412 | 0.0000752935 | 0.9999902473 | 0.0146800000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1592310750 |
| GSE13712_SHEAR | Down | -0.9450775115 |
| GSE13712_STATIC | Down | -1.3545404629 |
| GSE19018 | Down | -0.1398474582 |
| GSE19899_A1 | Down | -1.0450750652 |
| GSE19899_A2 | Down | -2.4177107376 |
| PubMed_21979375_A1 | Down | -1.7306963795 |
| PubMed_21979375_A2 | Down | -2.8596200057 |
| GSE35957 | Down | -2.4630841948 |
| GSE36640 | Down | -3.5457277766 |
| GSE54402 | Down | -0.7555958794 |
| GSE9593 | Down | -1.2786454168 |
| GSE43922 | Down | -0.2658771792 |
| GSE24585 | Up | 0.0107778536 |
| GSE37065 | Down | -0.1221956676 |
| GSE28863_A1 | Down | -0.2653415439 |
| GSE28863_A2 | Up | 0.0814661375 |
| GSE28863_A3 | Down | -0.1709521007 |
| GSE28863_A4 | Up | 0.0532835043 |
| GSE48662 | Down | -1.3085923356 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016342 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024463 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026297 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-320a | MIMAT0000510 | MIRT044740 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
