HCSGD entry for SUV420H2
1. General information
| Official gene symbol | SUV420H2 |
|---|---|
| Entrez ID | 84787 |
| Gene full name | suppressor of variegation 4-20 homolog 2 (Drosophila) |
| Other gene symbols | KMT5C |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000780 | Condensed nuclear chromosome, centromeric region | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005720 | Nuclear heterochromatin | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0034773 | Histone H4-K20 trimethylation | IEA | biological_process |
| GO:0042799 | Histone methyltransferase activity (H4-K20 specific) | IEA | molecular_function |
| GO:0070087 | Chromo shadow domain binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7457313324 | 0.6458486912 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0069469792 |
| GSE13712_SHEAR | Down | -0.0928744419 |
| GSE13712_STATIC | Down | -0.2348725169 |
| GSE19018 | Up | 0.0906237512 |
| GSE19899_A1 | Down | -0.0572822633 |
| GSE19899_A2 | Up | 0.0852780689 |
| PubMed_21979375_A1 | Down | -0.1588733498 |
| PubMed_21979375_A2 | Down | -0.0100645453 |
| GSE35957 | Up | 0.0950908104 |
| GSE36640 | Down | -0.0239680026 |
| GSE54402 | Down | -0.0004513761 |
| GSE9593 | Up | 0.0985752315 |
| GSE43922 | Up | 0.1178057970 |
| GSE24585 | Up | 0.0498082892 |
| GSE37065 | Down | -0.0821726603 |
| GSE28863_A1 | Down | -0.2265247505 |
| GSE28863_A2 | Down | -0.1193282745 |
| GSE28863_A3 | Up | 0.2747775915 |
| GSE28863_A4 | Up | 0.0820600882 |
| GSE48662 | Up | 0.0966231139 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | MIRT020409 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-29a-3p | MIMAT0000086 | MIRT049978 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
