HCSGD entry for CBR4
1. General information
| Official gene symbol | CBR4 |
|---|---|
| Entrez ID | 84869 |
| Gene full name | carbonyl reductase 4 |
| Other gene symbols | SDR45C1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003955 | NAD(P)H dehydrogenase (quinone) activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005759 | Mitochondrial matrix | IDA ISS | cellular_component |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0008753 | NADPH dehydrogenase (quinone) activity | IDA ISS | molecular_function |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0044597 | Daunorubicin metabolic process | IMP | biological_process |
| GO:0044598 | Doxorubicin metabolic process | IMP | biological_process |
| GO:0048038 | Quinone binding | IDA ISS | molecular_function |
| GO:0051289 | Protein homotetramerization | IPI | biological_process |
| GO:0070402 | NADPH binding | IDA ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8384207705 | 0.3015134683 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1288355238 |
| GSE13712_SHEAR | Up | 0.0307986445 |
| GSE13712_STATIC | Down | -0.0004986734 |
| GSE19018 | Down | -0.0560693272 |
| GSE19899_A1 | Up | 0.0550271588 |
| GSE19899_A2 | Down | -0.1733132472 |
| PubMed_21979375_A1 | Down | -0.1197041994 |
| PubMed_21979375_A2 | Down | -0.0229657355 |
| GSE35957 | Down | -0.4162905850 |
| GSE36640 | Up | 0.0263158536 |
| GSE54402 | Down | -0.2349689473 |
| GSE9593 | Down | -0.5444467965 |
| GSE43922 | Up | 0.0813356673 |
| GSE24585 | Up | 0.0285856187 |
| GSE37065 | Up | 0.1071373989 |
| GSE28863_A1 | Up | 0.0443068476 |
| GSE28863_A2 | Down | -0.1699896778 |
| GSE28863_A3 | Down | -0.3276087949 |
| GSE28863_A4 | Down | -0.1533329024 |
| GSE48662 | Up | 0.4491251391 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020570 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020570 | Reporter assay;Other | Non-Functional MTI | 20584899 |
| hsa-miR-1 | MIMAT0000416 | MIRT023498 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032121 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
