HCSGD entry for LINGO1


1. General information

Official gene symbolLINGO1
Entrez ID84894
Gene full nameleucine rich repeat and Ig domain containing 1
Other gene symbolsLERN1 LRRN6A UNQ201
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005154Epidermal growth factor receptor bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0021954Central nervous system neuron developmentIEAbiological_process
GO:0031175Neuron projection developmentIEAbiological_process
GO:0043491Protein kinase B signalingIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048715Negative regulation of oligodendrocyte differentiationIEAbiological_process
GO:0050770Regulation of axonogenesisTASbiological_process
GO:0050771Negative regulation of axonogenesisTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75347717790.28112667070.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3893512725
GSE13712_SHEARDown-0.9053314809
GSE13712_STATICDown-0.2047680499
GSE19018Up0.0254371309
GSE19899_A1Down-0.0308941488
GSE19899_A2Up0.0838481682
PubMed_21979375_A1Up0.1771487440
PubMed_21979375_A2Down-0.0338206915
GSE35957Up0.0645201998
GSE36640Up0.1219204001
GSE54402Down-0.0591426095
GSE9593Down-0.4144729814
GSE43922Up0.0088629552
GSE24585Down-0.4429752997
GSE37065Up0.0516382114
GSE28863_A1Down-0.1329033802
GSE28863_A2Down-0.0560991184
GSE28863_A3Up0.2499298296
GSE28863_A4Up0.0131915196
GSE48662Up0.2409100386

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.