HCSGD entry for CNTNAP1
1. General information
| Official gene symbol | CNTNAP1 |
|---|---|
| Entrez ID | 8506 |
| Gene full name | contactin associated protein 1 |
| Other gene symbols | CASPR CNTNAP NRXN4 P190 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002175 | Protein localization to paranode region of axon | ISS | biological_process |
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007010 | Cytoskeleton organization | ISS | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | ISS | cellular_component |
| GO:0008088 | Axon cargo transport | ISS | biological_process |
| GO:0009967 | Positive regulation of signal transduction | TAS | biological_process |
| GO:0016021 | Integral component of membrane | ISS | cellular_component |
| GO:0017124 | SH3 domain binding | ISS | molecular_function |
| GO:0019227 | Neuronal action potential propagation | ISS | biological_process |
| GO:0030913 | Paranodal junction assembly | ISS | biological_process |
| GO:0033270 | Paranode region of axon | ISS | cellular_component |
| GO:0048812 | Neuron projection morphogenesis | ISS | biological_process |
| GO:0050884 | Neuromuscular process controlling posture | IEA | biological_process |
| GO:0050885 | Neuromuscular process controlling balance | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1274899700 | 0.0350480187 | 0.7269485170 | 0.3538545838 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7478326845 |
| GSE13712_SHEAR | Down | -0.0472587414 |
| GSE13712_STATIC | Down | -0.2530162001 |
| GSE19018 | Up | 0.2159065853 |
| GSE19899_A1 | Down | -0.4677403512 |
| GSE19899_A2 | Down | -0.4882440328 |
| PubMed_21979375_A1 | Down | -0.4523244904 |
| PubMed_21979375_A2 | Down | -0.2951231195 |
| GSE35957 | Down | -0.0261261538 |
| GSE36640 | Up | 1.0316159661 |
| GSE54402 | Down | -0.6098087616 |
| GSE9593 | Up | 0.1042523157 |
| GSE43922 | Down | -0.8875034181 |
| GSE24585 | Up | 0.2946466788 |
| GSE37065 | Down | -0.3905015888 |
| GSE28863_A1 | Up | 1.3353767952 |
| GSE28863_A2 | Up | 1.0170039658 |
| GSE28863_A3 | Up | 0.0825444378 |
| GSE28863_A4 | Up | 0.0723249738 |
| GSE48662 | Down | -0.2580195897 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021803 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
