HCSGD entry for ITGA8
1. General information
| Official gene symbol | ITGA8 |
|---|---|
| Entrez ID | 8516 |
| Gene full name | integrin, alpha 8 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001656 | Metanephros development | IEA | biological_process |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007160 | Cell-matrix adhesion | NAS | biological_process |
| GO:0007229 | Integrin-mediated signaling pathway | IEA | biological_process |
| GO:0007420 | Brain development | IEA | biological_process |
| GO:0007613 | Memory | IEA | biological_process |
| GO:0008305 | Integrin complex | TAS | cellular_component |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0016337 | Cell-cell adhesion | NAS | biological_process |
| GO:0030030 | Cell projection organization | IEA | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030511 | Positive regulation of transforming growth factor beta receptor signaling pathway | IEA | biological_process |
| GO:0032591 | Dendritic spine membrane | IEA | cellular_component |
| GO:0034678 | Alpha8-beta1 integrin complex | TAS | cellular_component |
| GO:0042472 | Inner ear morphogenesis | IEA | biological_process |
| GO:0043204 | Perikaryon | IEA | cellular_component |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0045184 | Establishment of protein localization | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048745 | Smooth muscle tissue development | IEA | biological_process |
| GO:2000721 | Positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2223872953 | 0.0167672391 | 0.9034505325 | 0.2533083764 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0286648902 |
| GSE13712_SHEAR | Down | -0.0596682050 |
| GSE13712_STATIC | Up | 0.0303340468 |
| GSE19018 | Up | 0.1134280878 |
| GSE19899_A1 | Down | -0.0164221774 |
| GSE19899_A2 | Down | -0.3991596273 |
| PubMed_21979375_A1 | Down | -0.1844069324 |
| PubMed_21979375_A2 | Down | -0.0805050076 |
| GSE35957 | Up | 0.5844366414 |
| GSE36640 | Up | 3.0116437901 |
| GSE54402 | Down | -0.1981928284 |
| GSE9593 | Up | 0.8565934056 |
| GSE43922 | Down | -0.0526023616 |
| GSE24585 | Down | -0.2286444507 |
| GSE37065 | Down | -0.3724736776 |
| GSE28863_A1 | Down | -0.5896492774 |
| GSE28863_A2 | Down | -1.4565943485 |
| GSE28863_A3 | Down | -0.8836596431 |
| GSE28863_A4 | Down | -0.0230732668 |
| GSE48662 | Up | 0.7054864934 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040247 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047150 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
