HCSGD entry for CAV2


1. General information

Official gene symbolCAV2
Entrez ID858
Gene full namecaveolin 2
Other gene symbolsCAV
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0001937Negative regulation of endothelial cell proliferationIEA ISSbiological_process
GO:0001938Positive regulation of endothelial cell proliferationIEAbiological_process
GO:0002080Acrosomal membraneIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIDAcellular_component
GO:0005634NucleusIEAcellular_component
GO:0005794Golgi apparatusISScellular_component
GO:0005811Lipid particleIEAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0005901CaveolaIDA IEAcellular_component
GO:0006906Vesicle fusionIDAbiological_process
GO:0007005Mitochondrion organizationIEA ISSbiological_process
GO:0007029Endoplasmic reticulum organizationIEA ISSbiological_process
GO:0007088Regulation of mitosisIEPbiological_process
GO:0007268Synaptic transmissionIEAbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0016020MembraneIDAcellular_component
GO:0016050Vesicle organizationIDAbiological_process
GO:0019905Syntaxin bindingIEAmolecular_function
GO:0030133Transport vesicleIDAcellular_component
GO:0030512Negative regulation of transforming growth factor beta receptor signaling pathwayIEAbiological_process
GO:0031234Extrinsic component of cytoplasmic side of plasma membraneIDAcellular_component
GO:0031410Cytoplasmic vesicleIDAcellular_component
GO:0031748D1 dopamine receptor bindingIPImolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043234Protein complexIEAcellular_component
GO:0045121Membrane raftIDAcellular_component
GO:0048278Vesicle dockingIDAbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0048741Skeletal muscle fiber developmentIEA ISSbiological_process
GO:0051219Phosphoprotein bindingIEAmolecular_function
GO:0051259Protein oligomerizationIEAbiological_process
GO:0060161Positive regulation of dopamine receptor signaling pathwayIMPbiological_process
GO:0070836Caveola assemblyIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73557498200.01316918810.99999024730.2258842448

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2618582736
GSE13712_SHEARDown-0.1339723803
GSE13712_STATICDown-0.1736953238
GSE19018Up0.6911564403
GSE19899_A1Down-0.5756495469
GSE19899_A2Down-1.0588611687
PubMed_21979375_A1Down-1.7032363952
PubMed_21979375_A2Down-1.1428796830
GSE35957Up0.3143948747
GSE36640Up1.3167685541
GSE54402Down-1.4908825659
GSE9593Up0.1271699057
GSE43922Down-0.4930566628
GSE24585Up0.0175685460
GSE37065Down-0.1419877104
GSE28863_A1Down-0.2943729943
GSE28863_A2Down-0.0638839521
GSE28863_A3Up0.1780310683
GSE28863_A4Down-0.0035495822
GSE48662Down-0.2733419108

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-199a-3pMIMAT0000232MIRT006655Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI21807947
hsa-miR-93-5pMIMAT0000093MIRT028136SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029751MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.