HCSGD entry for SKAP1
1. General information
| Official gene symbol | SKAP1 |
|---|---|
| Entrez ID | 8631 |
| Gene full name | src kinase associated phosphoprotein 1 |
| Other gene symbols | SCAP1 SKAP55 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005070 | SH3/SH2 adaptor activity | IC | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0009967 | Positive regulation of signal transduction | IC | biological_process |
| GO:0017124 | SH3 domain binding | TAS | molecular_function |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0019903 | Protein phosphatase binding | IPI | molecular_function |
| GO:0032403 | Protein complex binding | IEA | molecular_function |
| GO:0042169 | SH2 domain binding | IDA IEA | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IMP | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0050852 | T cell receptor signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5349996809 | 0.7807605258 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0512821350 |
| GSE13712_SHEAR | Up | 0.1506857964 |
| GSE13712_STATIC | Up | 0.1168940547 |
| GSE19018 | Up | 0.1562541463 |
| GSE19899_A1 | Down | -0.0228164078 |
| GSE19899_A2 | Down | -0.0789511378 |
| PubMed_21979375_A1 | Down | -0.0307733061 |
| PubMed_21979375_A2 | Down | -0.0007592488 |
| GSE35957 | Down | -0.0866099234 |
| GSE36640 | Up | 0.2030691907 |
| GSE54402 | Up | 0.0321948154 |
| GSE9593 | Up | 0.1700728182 |
| GSE43922 | Up | 0.0135543425 |
| GSE24585 | Down | -0.0064067376 |
| GSE37065 | Down | -0.0693667286 |
| GSE28863_A1 | Down | -0.2309001676 |
| GSE28863_A2 | Down | -0.2350162102 |
| GSE28863_A3 | Up | 0.3838166060 |
| GSE28863_A4 | Up | 0.2262145233 |
| GSE48662 | Up | 0.0120924083 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
