HCSGD entry for AOC3

1. General information

Official gene symbolAOC3
Entrez ID8639
Gene full nameamine oxidase, copper containing 3
Other gene symbolsHPAO SSAO VAP-1 VAP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005261Cation channel activityIDAmolecular_function
GO:0005507Copper ion bindingIDA IEAmolecular_function
GO:0005509Calcium ion bindingIDAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005902MicrovillusIDAcellular_component
GO:0006810TransportIDAbiological_process
GO:0006812Cation transportIDAbiological_process
GO:0006954Inflammatory responseTASbiological_process
GO:0007155Cell adhesionIDAbiological_process
GO:0008131Primary amine oxidase activityIDA IEAmolecular_function
GO:0009308Amine metabolic processIDA IEAbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0016021Integral component of membraneIDAcellular_component
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0042803Protein homodimerization activityTASmolecular_function
GO:0046677Response to antibioticIDAbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0048038Quinone bindingIDA IEAmolecular_function
GO:0052593Tryptamine:oxygen oxidoreductase (deaminating) activityIEAmolecular_function
GO:0052594Aminoacetone:oxygen oxidoreductase(deaminating) activityIEAmolecular_function
GO:0052595Aliphatic-amine oxidase activityIEAmolecular_function
GO:0052596Phenethylamine:oxygen oxidoreductase (deaminating) activityIEAmolecular_function
GO:0055085Transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12308772080.24580377270.71750927810.9542931268

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3693379323
GSE13712_SHEARDown-0.1870828481
GSE13712_STATICUp0.0785931792
GSE19018Up0.0540099655
GSE19899_A1Up0.0406968067
GSE19899_A2Up0.5678713573
PubMed_21979375_A1Up0.7404888434
PubMed_21979375_A2Up0.4914859406
GSE35957Down-0.2638766652
GSE36640Up0.5623736385
GSE54402Up0.4568337076
GSE9593Down-3.1036793301
GSE43922Up0.0135178043
GSE24585Down-0.6739063499
GSE37065Up0.4462700479
GSE28863_A1Up0.0278950489
GSE28863_A2Up0.1741424365
GSE28863_A3Up0.3339234236
GSE28863_A4Up0.0953296101
GSE48662Down-0.0006161832

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PhenelzineDB00780 APRD00099
6-hydroxydopa quinoneDB04334 EXPT03094

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.