HCSGD entry for CBR1
1. General information
| Official gene symbol | CBR1 |
|---|---|
| Entrez ID | 873 |
| Gene full name | carbonyl reductase 1 |
| Other gene symbols | CBR SDR21C1 hCBR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004090 | Carbonyl reductase (NADPH) activity | IDA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0016655 | Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | IDA | molecular_function |
| GO:0017144 | Drug metabolic process | IDA | biological_process |
| GO:0019369 | Arachidonic acid metabolic process | TAS | biological_process |
| GO:0019371 | Cyclooxygenase pathway | TAS | biological_process |
| GO:0042373 | Vitamin K metabolic process | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047021 | 15-hydroxyprostaglandin dehydrogenase (NADP+) activity | IEA | molecular_function |
| GO:0050221 | Prostaglandin-E2 9-reductase activity | IEA | molecular_function |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3466665818 | 0.1851438927 | 0.9999902473 | 0.8341616570 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1878220565 |
| GSE13712_SHEAR | Down | -0.1946090594 |
| GSE13712_STATIC | Down | -0.1785799263 |
| GSE19018 | Down | -0.3107239185 |
| GSE19899_A1 | Down | -0.0842949926 |
| GSE19899_A2 | Down | -0.0895969481 |
| PubMed_21979375_A1 | Up | 0.3629496003 |
| PubMed_21979375_A2 | Down | -0.8297963268 |
| GSE35957 | Down | -0.6719572282 |
| GSE36640 | Down | -0.1072860055 |
| GSE54402 | Up | 0.3308234977 |
| GSE9593 | Up | 0.1549298022 |
| GSE43922 | Up | 0.0443221881 |
| GSE24585 | Down | -0.1643263089 |
| GSE37065 | Up | 0.2970730128 |
| GSE28863_A1 | Up | 0.0969146609 |
| GSE28863_A2 | Up | 0.4525712412 |
| GSE28863_A3 | Down | -0.5433320769 |
| GSE28863_A4 | Up | 0.2506455749 |
| GSE48662 | Down | -0.0885324249 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 | DB03556 | EXPT02539 |
| 3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol | DB04463 | EXPT00389 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038897 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042005 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045152 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049536 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
