HCSGD entry for SUCLG1
1. General information
| Official gene symbol | SUCLG1 |
|---|---|
| Entrez ID | 8802 |
| Gene full name | succinate-CoA ligase, alpha subunit |
| Other gene symbols | GALPHA MTDPS9 SUCLA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003878 | ATP citrate synthase activity | IEA | molecular_function |
| GO:0004775 | Succinate-CoA ligase (ADP-forming) activity | IEA | molecular_function |
| GO:0004776 | Succinate-CoA ligase (GDP-forming) activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006099 | Tricarboxylic acid cycle | IEA TAS | biological_process |
| GO:0006104 | Succinyl-CoA metabolic process | IEA | biological_process |
| GO:0006105 | Succinate metabolic process | IEA | biological_process |
| GO:0019003 | GDP binding | IEA | molecular_function |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045244 | Succinate-CoA ligase complex (GDP-forming) | IEA | cellular_component |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
| GO:0048037 | Cofactor binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9262946431 | 0.3281943733 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0816420901 |
| GSE13712_SHEAR | Up | 0.0025961022 |
| GSE13712_STATIC | Down | -0.0885158497 |
| GSE19018 | Up | 0.2256333842 |
| GSE19899_A1 | Down | -0.1872125687 |
| GSE19899_A2 | Down | -0.0841194246 |
| PubMed_21979375_A1 | Down | -0.1913779965 |
| PubMed_21979375_A2 | Down | -0.0210838244 |
| GSE35957 | Down | -0.0778599851 |
| GSE36640 | Up | 0.0646721916 |
| GSE54402 | Up | 0.0196019032 |
| GSE9593 | Down | -0.3605094098 |
| GSE43922 | Down | -0.0368922700 |
| GSE24585 | Up | 0.0619699107 |
| GSE37065 | Down | -0.2841908935 |
| GSE28863_A1 | Up | 0.0339267005 |
| GSE28863_A2 | Up | 0.2715614362 |
| GSE28863_A3 | Down | -0.4211241378 |
| GSE28863_A4 | Down | -0.0861042099 |
| GSE48662 | Down | -0.0289163614 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-423-3p | MIMAT0001340 | MIRT042588 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042752 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049513 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
