HCSGD entry for ACTN3
1. General information
| Official gene symbol | ACTN3 |
|---|---|
| Entrez ID | 89 |
| Gene full name | actinin, alpha 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005178 | Integrin binding | TAS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005884 | Actin filament | TAS | cellular_component |
| GO:0005925 | Focal adhesion | IMP | cellular_component |
| GO:0008307 | Structural constituent of muscle | TAS | molecular_function |
| GO:0030049 | Muscle filament sliding | TAS | biological_process |
| GO:0031143 | Pseudopodium | TAS | cellular_component |
| GO:0042803 | Protein homodimerization activity | TAS | molecular_function |
| GO:0042981 | Regulation of apoptotic process | NAS | biological_process |
| GO:0048041 | Focal adhesion assembly | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8079241860 | 0.5532166939 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1168059724 |
| GSE13712_SHEAR | Up | 0.0064532332 |
| GSE13712_STATIC | Up | 0.0633400559 |
| GSE19018 | Up | 0.1309622876 |
| GSE19899_A1 | Down | -0.1955661199 |
| GSE19899_A2 | Up | 0.0178149224 |
| PubMed_21979375_A1 | Down | -0.3425409511 |
| PubMed_21979375_A2 | Up | 0.0438425188 |
| GSE35957 | Up | 0.0947903764 |
| GSE36640 | Up | 0.0876827401 |
| GSE54402 | Up | 0.0780966010 |
| GSE9593 | Up | 0.0396570581 |
| GSE43922 | Up | 0.0233359994 |
| GSE24585 | Down | -0.0001180487 |
| GSE37065 | Down | -0.0602785789 |
| GSE28863_A1 | Down | -0.0805353968 |
| GSE28863_A2 | Down | -0.0825787865 |
| GSE28863_A3 | Up | 0.1232478570 |
| GSE28863_A4 | Up | 0.0519519554 |
| GSE48662 | Up | 0.0126415221 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
