HCSGD entry for CCNC

1. General information

Official gene symbolCCNC
Entrez ID892
Gene full namecyclin C
Other gene symbolsCycC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000079Regulation of cyclin-dependent protein serine/threonine kinase activityIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0006351Transcription, DNA-templatedTASbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0007179Transforming growth factor beta receptor signaling pathwayTASbiological_process
GO:0007219Notch signaling pathwayTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016591DNA-directed RNA polymerase II, holoenzymeIEAcellular_component
GO:0016592Mediator complexIEAcellular_component
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98611915200.05600224540.99999024730.4446561388

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0249277412
GSE13712_SHEARDown-0.1172618733
GSE13712_STATICDown-0.0685029400
GSE19018Up0.0734115327
GSE19899_A1Down-0.3969626090
GSE19899_A2Down-0.3352329642
PubMed_21979375_A1Up0.0177933499
PubMed_21979375_A2Down-0.2969958094
GSE35957Up0.1284769599
GSE36640Down-0.1069971429
GSE54402Down-0.1655499196
GSE9593Down-0.0192117279
GSE43922Down-0.3986696645
GSE24585Down-0.1695050314
GSE37065Down-0.1715722956
GSE28863_A1Down-0.1108120025
GSE28863_A2Up0.1217203882
GSE28863_A3Down-0.4736969324
GSE28863_A4Down-0.1630626714
GSE48662Down-0.3744492770

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019265MicroarrayFunctional MTI (Weak)17612493
hsa-let-7c-5pMIMAT0000064MIRT051792CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.