HCSGD entry for PLCZ1

1. General information

Official gene symbolPLCZ1
Entrez ID89869
Gene full namephospholipase C, zeta 1
Other gene symbolsNYD-SP27 PLC-zeta-1 PLCzeta
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004435Phosphatidylinositol phospholipase C activityIEAmolecular_function
GO:0004629Phospholipase C activityIEAmolecular_function
GO:0004871Signal transducer activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005829CytosolIEA TAScellular_component
GO:0006629Lipid metabolic processIEAbiological_process
GO:0006816Calcium ion transportIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007343Egg activationIEAbiological_process
GO:0016042Lipid catabolic processIEAbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0043647Inositol phosphate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53724139660.77038361760.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1391840941
GSE13712_SHEARDown-0.0175047396
GSE13712_STATICDown-0.0324008127
GSE19018Down-0.0098574981
GSE19899_A1Down-0.0774950278
GSE19899_A2Up0.4895917762
PubMed_21979375_A1Up0.4239906963
PubMed_21979375_A2Up0.5632536602
GSE35957Down-0.0989234044
GSE36640Down-0.1473882100
GSE54402Up0.1735791059
GSE9593Up0.0893650682
GSE43922Up0.0090037519
GSE24585Down-0.2815800484
GSE37065Down-0.0674134780
GSE28863_A1Down-0.0298411352
GSE28863_A2Down-0.1168430148
GSE28863_A3Up0.1266312857
GSE28863_A4Down-0.0314340090
GSE48662Up0.0495910536

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.