HCSGD entry for RHOT2
1. General information
| Official gene symbol | RHOT2 |
|---|---|
| Entrez ID | 89941 |
| Gene full name | ras homolog family member T2 |
| Other gene symbols | ARHT2 C16orf39 MIRO-2 MIRO2 RASL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA TAS | biological_process |
| GO:0019725 | Cellular homeostasis | IEA IMP | biological_process |
| GO:0031307 | Integral component of mitochondrial outer membrane | IDA | cellular_component |
| GO:0047497 | Mitochondrion transport along microtubule | IMP | biological_process |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
| GO:0097345 | Mitochondrial outer membrane permeabilization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8786320011 | 0.2116801603 | 0.9999902473 | 0.8879755538 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1607187418 |
| GSE13712_SHEAR | Down | -0.0495630153 |
| GSE13712_STATIC | Down | -0.1963954298 |
| GSE19018 | Down | -0.1347872684 |
| GSE19899_A1 | Down | -0.0610917294 |
| GSE19899_A2 | Up | 0.0507202160 |
| PubMed_21979375_A1 | Down | -0.0183410703 |
| PubMed_21979375_A2 | Up | 0.1352893292 |
| GSE35957 | Down | -0.3774958120 |
| GSE36640 | Down | -0.3293641019 |
| GSE54402 | Up | 0.2177921776 |
| GSE9593 | Down | -0.5377199305 |
| GSE43922 | Up | 0.1072704343 |
| GSE24585 | Down | -0.4649018562 |
| GSE37065 | Down | -0.1460393585 |
| GSE28863_A1 | Up | 0.0842247108 |
| GSE28863_A2 | Up | 0.1169473123 |
| GSE28863_A3 | Up | 0.2781568237 |
| GSE28863_A4 | Up | 0.0886263264 |
| GSE48662 | Down | -0.0828758136 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030517 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-760 | MIMAT0004957 | MIRT036780 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049436 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
