HCSGD entry for LACRT

1. General information

Official gene symbolLACRT
Entrez ID90070
Gene full namelacritin
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001948Glycoprotein bindingIDAmolecular_function
GO:0001968Fibronectin bindingIDAmolecular_function
GO:0005518Collagen bindingIDAmolecular_function
GO:0005576Extracellular regionIDAcellular_component
GO:0008083Growth factor activityIDAmolecular_function
GO:0008284Positive regulation of cell proliferationIDAbiological_process
GO:0019722Calcium-mediated signalingIDAbiological_process
GO:0030141Secretory granuleIDAcellular_component
GO:0033173Calcineurin-NFAT signaling cascadeIDAbiological_process
GO:0034067Protein localization to Golgi apparatusIDAbiological_process
GO:0043237Laminin-1 bindingIDAmolecular_function
GO:0047485Protein N-terminus bindingIPImolecular_function
GO:0050679Positive regulation of epithelial cell proliferationIDAbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0051047Positive regulation of secretionIDAbiological_process
GO:0051281Positive regulation of release of sequestered calcium ion into cytosolIDAbiological_process
GO:0051533Positive regulation of NFAT protein import into nucleusIDAbiological_process
GO:0070075Tear secretionNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54571096460.89342895410.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0654465643
GSE13712_SHEARUp0.1388157582
GSE13712_STATICUp0.0986117438
GSE19018Up0.1649805160
GSE19899_A1Up0.1184881998
GSE19899_A2Down-0.0648577693
PubMed_21979375_A1Up0.0884224139
PubMed_21979375_A2Up0.0917396453
GSE35957Up0.0373306212
GSE36640Up0.0836634477
GSE54402Up0.0254773649
GSE9593Up0.0863863024
GSE43922Up0.0191273486
GSE24585Down-0.2062349044
GSE37065Down-0.0175947240
GSE28863_A1Down-0.0523931006
GSE28863_A2Down-0.0753381831
GSE28863_A3Up0.1545038139
GSE28863_A4Up0.0327834937
GSE48662Up0.2076385296

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019336MicroarrayFunctional MTI (Weak)17612493
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.