HCSGD entry for CH25H
1. General information
| Official gene symbol | CH25H |
|---|---|
| Entrez ID | 9023 |
| Gene full name | cholesterol 25-hydroxylase |
| Other gene symbols | C25H |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001567 | Cholesterol 25-hydroxylase activity | IEA | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006629 | Lipid metabolic process | TAS | biological_process |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0006699 | Bile acid biosynthetic process | TAS | biological_process |
| GO:0008203 | Cholesterol metabolic process | IEA | biological_process |
| GO:0008206 | Bile acid metabolic process | TAS | biological_process |
| GO:0008395 | Steroid hydroxylase activity | TAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016126 | Sterol biosynthetic process | IEA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0787084913 | 0.3106974735 | 0.5909999715 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2142163842 |
| GSE13712_SHEAR | Down | -0.0261585484 |
| GSE13712_STATIC | Down | -0.4045115892 |
| GSE19018 | Down | -0.1130750085 |
| GSE19899_A1 | Down | -0.3518999692 |
| GSE19899_A2 | Down | -0.2537790477 |
| PubMed_21979375_A1 | Down | -0.3130629019 |
| PubMed_21979375_A2 | Up | 0.4188382820 |
| GSE35957 | Down | -0.3618627095 |
| GSE36640 | Up | 0.2180779184 |
| GSE54402 | Down | -0.3967100911 |
| GSE9593 | Up | 0.7513327975 |
| GSE43922 | Up | 0.0024630626 |
| GSE24585 | Down | -0.1307563091 |
| GSE37065 | Up | 1.1480626415 |
| GSE28863_A1 | Up | 0.1930543524 |
| GSE28863_A2 | Up | 0.8984307093 |
| GSE28863_A3 | Down | -0.0023113284 |
| GSE28863_A4 | Up | 0.2354261329 |
| GSE48662 | Up | 0.3788755095 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029826 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
