HCSGD entry for BRSK2

1. General information

Official gene symbolBRSK2
Entrez ID9024
Gene full nameBR serine/threonine kinase 2
Other gene symbolsC11orf7 PEN11B SAD1 STK29
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleIMPbiological_process
GO:0000287Magnesium ion bindingIDAmolecular_function
GO:0004674Protein serine/threonine kinase activityIDA IEAmolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0006468Protein phosphorylationIDAbiological_process
GO:0006887ExocytosisIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0007409AxonogenesisIEA ISSbiological_process
GO:0016301Kinase activityIEAmolecular_function
GO:0018105Peptidyl-serine phosphorylationIEAbiological_process
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0030010Establishment of cell polarityIEA ISSbiological_process
GO:0030182Neuron differentiationISSbiological_process
GO:0031532Actin cytoskeleton reorganizationIMPbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0050321Tau-protein kinase activityIDA IEA ISSmolecular_function
GO:0061178Regulation of insulin secretion involved in cellular response to glucose stimulusIEA IMP ISSbiological_process
GO:0070059Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38924483490.77681730560.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1104204342
GSE13712_SHEARUp0.2261445309
GSE13712_STATICDown-0.1771301960
GSE19018Up0.0242688377
GSE19899_A1Down-0.0368191296
GSE19899_A2Up0.1779519317
PubMed_21979375_A1Up0.3805281619
PubMed_21979375_A2Down-0.0102320474
GSE35957Up0.0828815314
GSE36640Down-0.1951967954
GSE54402Up0.1239902627
GSE9593Down-0.0070848321
GSE43922Up0.1827156781
GSE24585Down-0.4272037214
GSE37065Down-0.1216985265
GSE28863_A1Down-0.1406471276
GSE28863_A2Up0.0482343215
GSE28863_A3Up0.4807346715
GSE28863_A4Up0.0957198479
GSE48662Up0.1237559215

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029356MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.