HCSGD entry for FAM105B
1. General information
| Official gene symbol | FAM105B |
|---|---|
| Entrez ID | 90268 |
| Gene full name | family with sequence similarity 105, member B |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002040 | Sprouting angiogenesis | ISS | biological_process |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IMP | molecular_function |
| GO:0032088 | Negative regulation of NF-kappaB transcription factor activity | IDA IMP | biological_process |
| GO:0045087 | Innate immune response | IMP | biological_process |
| GO:0050728 | Negative regulation of inflammatory response | IMP | biological_process |
| GO:0060070 | Canonical Wnt signaling pathway | ISS | biological_process |
| GO:0070431 | Nucleotide-binding oligomerization domain containing 2 signaling pathway | IMP | biological_process |
| GO:0071797 | LUBAC complex | IEA | cellular_component |
| GO:1990108 | Protein linear deubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0488730215 | 0.8680858972 | 0.4870196442 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0372254029 |
| GSE13712_SHEAR | Up | 0.1251619700 |
| GSE13712_STATIC | Up | 0.1771181508 |
| GSE19018 | Down | -0.1128962156 |
| GSE19899_A1 | Up | 0.2784440276 |
| GSE19899_A2 | Up | 0.9348072073 |
| PubMed_21979375_A1 | Up | 0.8260885884 |
| PubMed_21979375_A2 | Up | 0.7531872620 |
| GSE35957 | Down | -0.2880479502 |
| GSE36640 | Down | -0.2175906630 |
| GSE54402 | Up | 0.4493549624 |
| GSE9593 | Down | -0.1913144889 |
| GSE43922 | Up | 0.4288271909 |
| GSE24585 | Down | -0.1341443935 |
| GSE37065 | Up | 0.1824225027 |
| GSE28863_A1 | Up | 0.4726085064 |
| GSE28863_A2 | Up | 0.5873120827 |
| GSE28863_A3 | Down | -0.3951496905 |
| GSE28863_A4 | Down | -0.1648521866 |
| GSE48662 | Down | -0.2716517056 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | MIRT020410 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020632 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028260 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT048714 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051214 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052362 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
