HCSGD entry for KLHL13
1. General information
| Official gene symbol | KLHL13 |
|---|---|
| Entrez ID | 90293 |
| Gene full name | kelch-like family member 13 |
| Other gene symbols | BKLHD2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000910 | Cytokinesis | IMP | biological_process |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9817826336 | 0.0000293340 | 0.9999902473 | 0.0094780488 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1473679365 |
| GSE13712_SHEAR | Down | -1.6480146799 |
| GSE13712_STATIC | Down | -0.8328085708 |
| GSE19018 | Down | -1.0368616164 |
| GSE19899_A1 | Down | -0.8377641342 |
| GSE19899_A2 | Down | -4.5189842942 |
| PubMed_21979375_A1 | Down | -2.2154334520 |
| PubMed_21979375_A2 | Down | -2.6337769353 |
| GSE35957 | Down | -1.1296565863 |
| GSE36640 | Down | -3.6599468246 |
| GSE54402 | Down | -2.6305547359 |
| GSE9593 | Down | -1.1547409777 |
| GSE43922 | Down | -1.9318294136 |
| GSE24585 | Down | -0.7231308004 |
| GSE37065 | Down | -0.0368487697 |
| GSE28863_A1 | Down | -0.0355068409 |
| GSE28863_A2 | Up | 0.1509428740 |
| GSE28863_A3 | Up | 0.1814461427 |
| GSE28863_A4 | Up | 0.4375097173 |
| GSE48662 | Down | -0.8658613270 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-218-5p | MIMAT0000275 | MIRT024225 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
