HCSGD entry for CCNT1
1. General information
| Official gene symbol | CCNT1 |
|---|---|
| Entrez ID | 904 |
| Gene full name | cyclin T1 |
| Other gene symbols | CCNT CYCT1 HIVE1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000079 | Regulation of cyclin-dependent protein serine/threonine kinase activity | IEA | biological_process |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0006468 | Protein phosphorylation | IPI | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | TAS | biological_process |
| GO:0008024 | Positive transcription elongation factor complex b | IDA | cellular_component |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0017069 | SnRNA binding | IEA | molecular_function |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0044212 | Transcription regulatory region DNA binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0050434 | Positive regulation of viral transcription | TAS | biological_process |
| GO:0051301 | Cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0470419057 | 0.8554191634 | 0.4802644436 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0803637651 |
| GSE13712_SHEAR | Up | 0.3351261808 |
| GSE13712_STATIC | Up | 0.1340094494 |
| GSE19018 | Down | -0.0798909058 |
| GSE19899_A1 | Up | 0.4813037947 |
| GSE19899_A2 | Up | 0.5373292421 |
| PubMed_21979375_A1 | Up | 0.1974419472 |
| PubMed_21979375_A2 | Up | 0.7475750809 |
| GSE35957 | Down | -0.2886352491 |
| GSE36640 | Up | 0.1059219495 |
| GSE54402 | Up | 0.2855001045 |
| GSE9593 | Down | -0.1185518997 |
| GSE43922 | Up | 0.4340523843 |
| GSE24585 | Up | 0.3435310503 |
| GSE37065 | Up | 0.0913550418 |
| GSE28863_A1 | Down | -0.0671909315 |
| GSE28863_A2 | Up | 0.2605960050 |
| GSE28863_A3 | Down | -1.0791138028 |
| GSE28863_A4 | Up | 0.1018288806 |
| GSE48662 | Up | 0.1815238756 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-27b-3p | MIMAT0000419 | MIRT006547 | Flow//Luciferase reporter assay//Microarray//qRT-PCR//Western blot | Functional MTI | 22205749 |
| hsa-miR-198 | MIMAT0000228 | MIRT004603 | Luciferase reporter assay | Functional MTI | 19148268 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
