HCSGD entry for ZNF622


1. General information

Official gene symbolZNF622
Entrez ID90441
Gene full namezinc finger protein 622
Other gene symbolsZPR9
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008631Intrinsic apoptotic signaling pathway in response to oxidative stressIDAbiological_process
GO:0033674Positive regulation of kinase activityIDAbiological_process
GO:0043065Positive regulation of apoptotic processIDAbiological_process
GO:0043410Positive regulation of MAPK cascadeIDAbiological_process
GO:0046330Positive regulation of JNK cascadeIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00374252880.92174919270.16409152821.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.9872449664
GSE13712_SHEARDown-0.0407227653
GSE13712_STATICUp0.1765732064
GSE19018Down-0.2079286701
GSE19899_A1Up0.7256282296
GSE19899_A2Up1.4631309927
PubMed_21979375_A1Up1.5881998471
PubMed_21979375_A2Up1.6814453420
GSE35957Up0.2656271817
GSE36640Up1.4675659741
GSE54402Up0.4237321619
GSE9593Up0.3957461160
GSE43922Up0.6669680495
GSE24585Down-0.0868663833
GSE37065Up0.0255328240
GSE28863_A1Down-0.3174675849
GSE28863_A2Up0.1157875732
GSE28863_A3Down-0.6315192345
GSE28863_A4Down-0.1163965513
GSE48662Up0.1560079232

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT001395pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT001395SequencingFunctional MTI (Weak)20371350
hsa-miR-1MIMAT0000416MIRT023928Proteomics;MicroarrayFunctional MTI (Weak)18668037
hsa-miR-103a-3pMIMAT0000101MIRT027111SequencingFunctional MTI (Weak)20371350
hsa-miR-92a-3pMIMAT0000092MIRT049311CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.