HCSGD entry for NFS1

1. General information

Official gene symbolNFS1
Entrez ID9054
Gene full nameNFS1 nitrogen fixation 1 homolog (S. cerevisiae)
Other gene symbolsIscS NIFS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000096Sulfur amino acid metabolic processTASbiological_process
GO:0003824Catalytic activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005739MitochondrionTAScellular_component
GO:0005759Mitochondrial matrixIDA IEA TAScellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0006461Protein complex assemblyTASbiological_process
GO:0006534Cysteine metabolic processIEAbiological_process
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006777Mo-molybdopterin cofactor biosynthetic processIEAbiological_process
GO:0018283Iron incorporation into metallo-sulfur clusterIDA IEAbiological_process
GO:0030170Pyridoxal phosphate bindingIEAmolecular_function
GO:0031071Cysteine desulfurase activityEXP IDA TASmolecular_function
GO:0032324Molybdopterin cofactor biosynthetic processTASbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13643206570.72661971050.74501686371.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1988573590
GSE13712_SHEARUp0.1837438835
GSE13712_STATICUp0.3928151220
GSE19018Up0.2516294245
GSE19899_A1Up0.1260445486
GSE19899_A2Up0.6741031425
PubMed_21979375_A1Up0.6117849379
PubMed_21979375_A2Down-0.2565261372
GSE35957Up0.0550826905
GSE36640Up0.5486226593
GSE54402Down-0.2487755904
GSE9593Up0.1238626488
GSE43922Up0.0456268571
GSE24585Down-0.0788190345
GSE37065Up0.0239518807
GSE28863_A1Down-0.0869586211
GSE28863_A2Down-0.1312129688
GSE28863_A3Down-0.6900760409
GSE28863_A4Up0.1172668126
GSE48662Up0.0715914217

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-CysteineDB00151 NUTR00018 | DB04443
L-AlanineDB00160 NUTR00013

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-222-3pMIMAT0000279MIRT046759CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.