HCSGD entry for CLDN12
1. General information
| Official gene symbol | CLDN12 |
|---|---|
| Entrez ID | 9069 |
| Gene full name | claudin 12 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005923 | Tight junction | IEA ISS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016338 | Calcium-independent cell-cell adhesion | ISS | biological_process |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0042802 | Identical protein binding | ISS | molecular_function |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
| GO:0070830 | Tight junction assembly | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0179229779 | 0.9910595038 | 0.3284121001 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2263687073 |
| GSE13712_SHEAR | Down | -0.2948714381 |
| GSE13712_STATIC | Up | 0.2493736898 |
| GSE19018 | Up | 0.4042771882 |
| GSE19899_A1 | Up | 0.3234413814 |
| GSE19899_A2 | Up | 0.8379794538 |
| PubMed_21979375_A1 | Up | 1.0766674384 |
| PubMed_21979375_A2 | Up | 0.2600345223 |
| GSE35957 | Up | 0.1097641163 |
| GSE36640 | Down | -0.0220806104 |
| GSE54402 | Up | 0.3502545989 |
| GSE9593 | Up | 0.1231211522 |
| GSE43922 | Up | 0.5500783533 |
| GSE24585 | Up | 0.2933254308 |
| GSE37065 | Up | 0.4488648866 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0767907919 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021304 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30b-5p | MIMAT0000420 | MIRT023422 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1 | MIMAT0000416 | MIRT023604 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-320b | MIMAT0005792 | MIRT036225 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044709 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
